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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIAA0776 All Species: 15.45
Human Site: S786 Identified Species: 28.33
UniProt: O94874 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O94874 NP_056138.1 794 89595 S786 I K D L V L K S R K S S V T E
Chimpanzee Pan troglodytes XP_518643 794 89625 S786 I K D L V L K S R K S S V T E
Rhesus Macaque Macaca mulatta XP_001100312 793 89480 R786 K D L V L K S R K S S V T E E
Dog Lupus familis XP_532236 830 93092 S822 I K D L I L K S R K S S V T E
Cat Felis silvestris
Mouse Mus musculus Q8CCJ3 793 89502 S785 I K D L V L K S R K S S V T E
Rat Rattus norvegicus B2GV24 793 89567 P785 I K D L V L K P R K S S V T E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510895 871 97174 P863 V K D L V L K P R K S S V T E
Chicken Gallus gallus Q5ZMG1 789 89086 P781 V K D L V L R P R K S S V T E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6PGY6 793 88661 Q786 I K D T V L A Q R K P S V T E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VI55 782 87464 A770 Q N Q V V E L A Q N F S R A S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q17750 735 80983 S728 M L V N D I S S L K Q S I M P
Sea Urchin Strong. purpuratus XP_780358 558 62888 K551 N N I R Q F I K G V K Q C S E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LX73 804 89055 L783 R I L T K R E L L E S Q M P L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 98.7 86 N.A. 90.5 90.6 N.A. 69.6 74.6 N.A. 62.9 N.A. 35.2 N.A. 23.6 35.8
Protein Similarity: 100 99.7 99.6 90.5 N.A. 95.9 96.4 N.A. 81.2 87.7 N.A. 80.2 N.A. 58.3 N.A. 43.9 52.7
P-Site Identity: 100 100 13.3 93.3 N.A. 100 93.3 N.A. 86.6 80 N.A. 73.3 N.A. 13.3 N.A. 20 6.6
P-Site Similarity: 100 100 33.3 100 N.A. 100 93.3 N.A. 93.3 93.3 N.A. 73.3 N.A. 33.3 N.A. 40 13.3
Percent
Protein Identity: N.A. N.A. N.A. 26.6 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 49.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 8 8 0 0 0 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % C
% Asp: 0 8 62 0 8 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 8 8 0 0 8 0 0 0 8 77 % E
% Phe: 0 0 0 0 0 8 0 0 0 0 8 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 47 8 8 0 8 8 8 0 0 0 0 0 8 0 0 % I
% Lys: 8 62 0 0 8 8 47 8 8 70 8 0 0 0 0 % K
% Leu: 0 8 16 54 8 62 8 8 16 0 0 0 0 0 8 % L
% Met: 8 0 0 0 0 0 0 0 0 0 0 0 8 8 0 % M
% Asn: 8 16 0 8 0 0 0 0 0 8 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 24 0 0 8 0 0 8 8 % P
% Gln: 8 0 8 0 8 0 0 8 8 0 8 16 0 0 0 % Q
% Arg: 8 0 0 8 0 8 8 8 62 0 0 0 8 0 0 % R
% Ser: 0 0 0 0 0 0 16 39 0 8 70 77 0 8 8 % S
% Thr: 0 0 0 16 0 0 0 0 0 0 0 0 8 62 0 % T
% Val: 16 0 8 16 62 0 0 0 0 8 0 8 62 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _